Review: Age-Related Macular Degeneration (AMD) is the leading cause of blindness in people over the age of 50. Every ten years after the age of 50 the prevalence of this disease increases exponentially. Many different factors contribute to the development of AMD, including genetic, environmental, and metabolic functions. In addition to smoking, abnormal blood pressure, and an unhealthy diet low in fruits and vegetables, many other studies are concluding that similar inflammatory and oxidative processes seen in other age-related diseases play a key role in the development of AMD. This disease affects the central areas of the retina and choroid. In return, central vision is impaired while peripheral vision is usually not lost. AMD comes in two different forms: the early non-neovascular (dry) type and the more advanced neovascular (wet) type. Each form has its own specific pathology and unique characteristics that differentiate them. Fatty and protein deposits called drusen may be the key risk factor in understanding the pathology, progression and treatment of dry AMD. Once more advanced wet AMD is diagnosed, pathology and treatment are aimed at the formation and destruction of abnormal blood vessels, characteristic of wet AMD eye. The increasing prevalence of AMD has influenced further investigations into which factors can be modulated to prevent the onset or halt the progression of AMD. Early diagnosis is very important because it is at this time that the ophthalmologist can detect the first signs of the disease through ultrasound or angiography. This text will discuss the pathology of drusen and the role of inflammation and oxidation in the aging eye. By better understanding these processes, more effective therapeutic and preventive approaches... the focus of the article... eh, Shane. "Age-related macular degeneration". Kerala Journal of Ophthamology: no. page Web.13. Moore, Kathryn J., and Ira Tabas. "Macrophages in the pathogenesis of atherosclerosis 16". Cell 145.3 (2011): 341-355. Print.14. Nicolosi, RJ "Consumption of 2 and 4 egg yolks/day for 5 weeks increases macular pigment concentrations in older adults with low macular pigment who take statins to lower cholesterol." American Journal of Clinical Nutrition 90: 1272-1279. Network. May 1, 2014.15. Sepici-Dincel, Aylin. “Choroidal neovascular membrane in age-related macular degeneration is associated with increased interleukin-6.” International Journal of Gerontology: 101-104. Network. May 1, 2014.16. Wang, Yadong. “An anti-angiogenic reverse thermal gel as a drug delivery system for wet age-related macular degeneration.” Macromolecular biosciences: 464-469. Network. May 1st 2014.