Topic > Pharmacogenomics Essay - 1133

Pharmacogenomics is the study of variation in human genomes and how they are affected by a response to drugs, due to heredity, which would be tailor-made to fit a person's genetic makeup person or population reduce morbidity caused by drugs. Pharmacogenetics, an older term, was constructed from the words pharmacology and genetics, now indicating the intersections between pharmaceuticals and genetics. The vision of pharmacogenomics offers safer and more effective drugs, where more people and populations use drug therapies which will increase the influence of clinical trials on the development of drugs and products used in clinical practice. (Mordini 2004) Patient selection must form an evidence base in pharmacogenomics testing in order to avoid genetic profiling, discrimination, stigmatization or distributional injustice. Pharmacogenomics tests provide information that could help in deciding treatment options for patients. Doctors cannot influence patients' decisions based on their own opinions. (Ndegwa 2007) In addition to ethical issues there are also social and legal issues. Social issues arising from pharmacogenomics testing could lead to unfair treatment or undesirable outcomes such as health discrepancies, due to medical coverage compared to others. Legal issues include how these pharmacogenomic effects are translated into practice. The Genetic Information Nondiscrimination Act passed in 2008 protects Americans from discrimination based on genetic information for health insurance and employment purposes. Along with these three issues there are also economic issues that compare whether the person would take full responsibility for billing for pharmacogenomic tests or whether insurance com...... middle of paper ...... in the facility of fluvoxamine; therefore it does not exist as an optical isomer. (Harten 1995) The active ingredient contained in this drug is fluvoxamine maleate. The chemical formula of fluvoxamine is C15H21F3N2O2 and must be stored at a freezer temperature of -20° C, in an inert atmosphere. The chemical property of this drug is colorless oil. Side effects associated with this drug are decreased appetite, sweating, nausea, anxiety, constipation, nervousness, unsteadiness, diarrhea, sexual dysfunction, insomnia, dry mouth, drowsiness, and dizziness. Additionally, abnormal bleeding, seizures, and manic episodes may be symptoms experienced while taking this medication. If a person were to stop taking the drug, they may also suffer from withdrawal symptoms such as chest pain, dizziness, tiredness, bad mood, nausea, vivid dreams, tingling in the extremities, and irritability..