The pancreas uses these two hormones to monitor blood glucose levels. After a meal, blood sugar usually rises. This is when insulin secretion will begin (Nussey S, Whitehead S. “Endocrinology: An Integrated Approach”). As a result, blood sugar returns to the normal range. This is how insulin maintains levels in the blood when it is high. However, when the blood level drops below the normal range, glucagon comes into play. Low blood glucose usually occurs when you are hungry and during physical activity. This will then activate glucagon secretion. When the blood level drops, the body enters an imbalance. This is why glucagon is essential to maintain homeostasis. The body will tell the pancreas to increase more glucose and the pancreas will secrete glucagon by taking glycogen from the liver to produce glucose. Glucose will produce energy and increase blood glucose concentrations (Homeostasis of Insulin and Glucose, Abpischools.org). When the pancreas fails to maintain homeostasis, many problems occur in the body. When the pancreas fails to produce insulin, type 1 and 2 diabetes can occur. For those with type 1 diabetes, insulin injections will be needed to regulate the blood glucose level, otherwise the glucose levels will be out of control. For type 2 diabetes, they are not as dependent on insulin as type 1, however, the body does not create enough of it in the body. When blood sugar