IndexIntroductionCase reportDiscussionConclusion Triple Due to its less distinct characteristics and variation in patterns, the patient remains undiagnosed. This disorder has broader socio-psychological implications on the patient's health. A case study on triple X syndrome (47, XXX) is compared with two other case studies of other previously published models. Infertility and amenorrhea appear to be the presenting characteristics of this syndrome. Cytogenetic analysis (karyotyping) revealed confirmation of triple X syndrome by the presence of an extra X chromosome. This study is aimed at exploring different models of triple X syndrome from a comparative study in order to enhance a better and deeper understanding of the disorder. Say no to plagiarism. Get a tailor-made essay on "Why Violent Video Games Shouldn't Be Banned"? Get an original essay Introduction Triple X syndrome is one of the most common genetic syndromes affecting females with a frequency of 1 in 1000 live female births. This syndrome is characterized by an extra X chromosome and therefore represented as 47, XXX. The disorder is said to occur due to a random error during meiotic division in the mother's or father's gametes. In some cases, the error occurs during the development of the embryo and this results in the mosaic pattern of triple X syndrome, in which only a few cells have an extra X chromosome. The following case study is of Triple of the mosaic Triple X (45, XO/ 47,XXX). Case ReportA 22 year old woman visited the outpatient department of Unani Regional Research Institute of Medicine (Unani Government Hospital, Chennai) complaining of no normal menstrual flow and inability to conceive with itching and skin lesions on extremities. His height was 5'1” and he weighed 44 kg at the time of his visit. She was conceived when her mother was 36 years old. She has 3 older sisters who all managed to conceive without any difficulty. No history of consanguineous marriages or genetic anomalies in the family. Menarche was at 12 years old. His academic record and intelligence quotient (IQ) were average and he had completed his education up to the 12th grade. She got married at 19 to a 28 year old male. Endocrinological testing revealed that her luteinizing hormone (LH) levels were 9.78 mIU/mL and follicle stimulating hormone (FSH) levels were 16.01 mIU/mL. His estradiol level was 22.10 pg/ml. Transvaginal ultrasound of the pelvis showed a retroverted uterus measuring 4 cm. The bottom end of the cavity contained an echogenic lesion measuring 1.2 × 0.8 cm. the right ovary appeared smaller than normal measuring 2.2 x 1.0 cm and no follicular activity was observed. The left ovary measured 2.2 × 1.0 cm and contained one follicle. Anti-Müllerian hormone (AMH) levels were less than 0.1 ng/ml (normal = 0.9-9.5 ng/ml). Karyotyping was performed using peripheral blood with G banding. 20 cells were counted and analyzed and all counted cells showed the presence of an extra X chromosome. Discussion In the case of patients with triple X syndrome (47, XXX) there are distinct symptoms. Young children show delayed language development. They show accelerated growth until puberty. Electroencephalogram (EEG) abnormalities appear.