Interestingly, no significant differences were identified between the experimental and comparison groups in terms of knowledge, adaptation and satisfaction with the program. However, diabetes self-care activities improved significantly (p = .02) for the experimental group (p. 316). Evidence Report Patients under the care of advanced practice nursing professionals who were advised to take a proactive role in developing the management plan under the supervision of their nurses and doctors. were more effective in their adhesion than those. Although no significant differences were found in outcomes that included A1C and triglyceride levels, notable increases occurred in patients adhering to activities related to self-care and willingness to make healthy lifestyle changes in areas of increased physical activity and nutritional intake. PICOT P ICOT question? This problem affects individuals with type II diabetes, their families, and their healthcare providers. The intervention identified as best practice focuses on direct nursing support as the most effective management in diabetic patients. Interventions focused on management strategies prescribed by nurses and doctors. Study results indicate that the use of direct patient support provided by nurses was more effective for compliance and improving diabetes management