The intense stimulant lysergic acid diethylamide (LSD) can briefly possess the mind of an individual who ingests it. As a result of its intensity and ability to open the “doors of recognition,” LSD could be violent to the psyche (Baker, 1999). It can take over the user's brain, tenderly uncovering life's dormant truths, or it can become enraged, reducing the user to a state of complete panic. Obviously, LSD should not be taken carelessly. This makes it especially scary to administer it to an unsuspecting individual, especially one who is unfamiliar with the properties of LSD. An individual unaccustomed to LSD and completely unaware that he has received a dose could be brought to the brink of mental collapse. In 1951, the Central Intelligence Agency (CIA) discovered that the Swiss pharmaceutical manufacturer Sandoz Pharmaceuticals had 100 million doses of LSD, accessible to any individual who wanted to purchase them. At the height of the Cold War, this was seen as a credible threat against the American public. The US Army purchased LSD and shortly thereafter military analysts and the CIA began Operation MKULTRA (Project MKULTRA, 1977). The experiments were primarily directed at willing and willing respondents in colleges, CIA laboratories, and independent research offices. However, some of these tests fell outside the bounds of adequate convention: one study tricked heroin addicts into participating as subjects by paying them in heroin, while another considered the impact of LSD on African American inmates in prison (Baker, 1999 ). . Military organizations needed to know to what extent it was possible to control human conduct through the use of psychoactive drugs such as LSD, mescaline, as well as the use of psychotropic drugs... middle of paper..., 12 - 26.Project MKULTRA, the CIA's behavior modification research program. (1977). In the US Senate. Washington, DC: United States Government.Freedman, B. (1987). Equipoise and the ethics of clinical research. New England Journal of Medicine, 48, 44-48.Miller, F. (2003). Therapeutic misunderstanding in the ethics of clinical trials. Hastings Center Report. Coleman, C. (2005). The ethics and regulation of research with human subjects. 3–50.50 Code of Federal Regulations, 46(102). Faden, R. (1986). History and theory of informed consent (pp. 114-159). New York, NY: Oxford University Press. Hoever, K. (2005). The ethics of research with biobanks: reason to question the importance attributed to informed consent. Archives of Internal Medicine, 165-198.Milgram, S. (1963). Behavioral study of obedience. Journal of Abnormal and Social Psychology, 67(4), 371-378